The idea that a pill could replace adequate exercise and healthy nutrition seems like the stuff of science fiction, but according to scientists at Washington University, a new pill really could prevent heart disease, dementia, and even build more muscle, by mimicking the effects of being active. Here’s what you need to know.
Scientists have created a compound called SLU-PP-332, and it works by activating specific proteins that are usually called upon by exercise. So far, experiments have been successful in rodent cells and the breakthrough might potentially result in future human applications that could make the population fitter and less likely to succumb to age or obesity related conditions such as diabetes and heart failure. The theory is that a drug able to replicate the effects of exercise could stave off muscle atrophy and weakness, and slow down or prevent the emergence of cancers and other ailments. But if you are thinking that a new ‘super’ pill could be an excuse to cancel your gym subscription, experts say you shouldn’t throw in the towel. “We cannot replace exercise; exercise is important on all levels,” said Bahaa Elgendy, the project’s principal investigator in a YouTube Q&A. “If I can exercise, I should go ahead and get the physical activity. But there are so many cases in which a substitute is needed.”
The researchers presented their results at the spring meeting of the American Chemical Society (ACS) this week and according to a press release, the metabolic changes associated with exercise kick off with the activation of specialized proteins known as estrogen-related receptors (ERRs), After around a decade of work, Elgendy and his colleagues developed a compound named SLU-PP-332, and it activates all three forms of ERR, including the most challenging target; ERRα. This type of ERR regulates exercise-induced body adaptations and other important physiological processes in the muscles. In experiments with mice, the team found that this compound increased a fatigue-resistant type of muscle fiber wihtout them doing any exercise, and also improved the animals’ endurance when they ran on a rodent treadmill. It goes without saying that it is early days for this potential ‘super pill,’ but if it can successfully translated to human use, it could have limitless potential for those who can’t exercise due to physical challenges, not to mention the potential buzz it could create in the world of supplements.
Introducing SLU-PP-332, a groundbreaking compound which was created to mimic the physiological effects of exercise without requiring extra time at the gym!
What does the science say?
Increased endurance: Mice treated with SLU-PP-332 ran up to 70% longer and 50% further than baseline performance.
We're not mice but it definitely warrants further reading.
Read the full study on endurance improvements
Weight loss without appetite change: After one month in clinical studies mice lost 12% of their body weight and gained 10 times less fat than control mice, with no change in food intake or exercise levels.
Again, we're not mice but it definitely warrants further reading.
See weight loss and fat reduction results study results here
Enhanced metabolic health: SLU-PP-332 was shown in studies to increase energy expenditure and fatty acid oxidation, mimicking the benefits of aerobic exercise and improving insulin sensitivity.
Explore the metabolic health benefits
If you're more of a listener and would like to see what the main youtube fitness influencers in the space have had to say about it then we've collated a list of the most popular videos!
Safest SLU-PP-332 Fat Burning Protocol (The Next BEST Thing?) Mitochondrial Health, Prevent Fat Gain – Vigorous Steve
https://youtu.be/4JOSPiXmkwU
Is SLU-PP-332 the Holy Grail of Fat Loss Supplements? – Jay Campbell + Hunter Williams
https://youtu.be/zCcL-KBVkQc
SLU-PP-332 For Fat Loss | A New Miracle Compound? – Hunter Williams
https://youtu.be/6PqkjvwrdXM
Get Ready for INSANE Fat Loss Results with GLP1's and SLU-PP-332! – Chase Irons
https://youtu.be/4vq-MZZoSoA
This product is sold as a research chemical only and not for human use.
