Oxytocin 10mg

Oxytocin peptide, often referred to as the “love hormone,” plays a crucial role in social bonding and attachment. It is released during moments of intimacy and has been linked to feelings of trust, empathy, and generosity. Research suggests that oxytocin may also have potential therapeutic applications for mental health disorders and improving social interactions

This product is sold as a research chemical and not for human use

Oxytocin is a neuropeptide hormone with therapeutic potential essential for life development. Australia Clinical studies have found a direct link between the nine amino acid peptide and reproductive functions, social bonding, role in social behaviour, and other biological functions.

The Oxytocin peptide has been shown to substantially impact human behaviour and physiology and has been found to play a major role in both partner and child relationships. The hypothalamus secretes this substance into the bloodstream from the pituitary gland in the brain. This peptide is also vital for father-child bonding and marital trust.

This peptide can regulate the brain-body connection. The hormone regulates muscle tone, bone density, and fat storage.

Oxytocin peptide has been shown to support a healthy immune system and mental performance in Australia research. For example, blood pressure, heart rate, and blood sugar are all regulated by oxytocin. In addition, the neuropeptide hormone has been linked to sexual arousal and memory formation

Memory

Early maternal deprivation has long been known to have a negative effect on lifelong cognitive functions and behaviours. According to research on mice, reduced parental attachment alters oxytocin levels. In one Australia experiment, maternally deprived mice treated with Oxytocin peptide had improved levels of hormones related to prefrontal neuron development [1].

It found that there was no overall behavioural difference; however, the oxytocin control group had improved cognitive performance compared to the placebo group [2]. Intranasal oxytocin administration improves learning in stressed mice, but only marginally.

Anxiety

Many Australia studies link the lack of oxytocin secretion to anxiety and sadness. For example, genetic variants in the oxytocin receptor gene have been related to social anxiety disorders and attachment problems in children. In addition, untreated social anxiety patients showed epigenetic alterations in the oxytocin receptor, suggesting a compensatory strategy for pathologically low oxytocin levels. This indicates that social anxiety could be a direct result of reduced oxytocin signalling [3].

Borderline personality disorder (BPD) has recently been connected to oxytocin dysregulation. People with BPD have altered non-verbal social behaviour and hypervigilance to hazards. These behaviours have been demonstrated to change with Oxytocin peptide therapy. For millions of people worldwide living with borderline personality disorder, even a small understanding of the pathophysiology that leads to BPD might help researchers improve their lives because currently it is notoriously difficult to treat [4]

Heart

Australia Researchers have suggested that oxytocin might help protect the heart and cardiovascular system by increasing the speed in which it takes to heal wounds and reduce inflammatory cytokines. In addition, if anxiety and fat can be reduced by taking oxytocin it could also be a valuable adjunct to present cardiovascular disease treatments [5].

Furthermore, there is also evidence that inhibiting the oxytocin receptor may cause atherosclerosis in specific situations. Conversely, increasing oxytocin levels in persons with low receptor density can protect the heart and reverse atherosclerosis.

In ischemia (heart attack), oxytocin infusion into the heart may preserve cardiomyocytes, the heart muscle cells, from apoptosis. In addition, prolonged oxytocin administration may help train cardiac stem cells to help regenerate tissue via direct differentiation, production of protective and cardiomyogenic factors, and their union with injured cardiomyocytes [6].

Further Australia research in mice shows that oxytocin peptide can prevent cardiac damage related to diabetes. During the experiment, mice treated with oxytocin experienced reduced body fat growth by 19% and fasting glucose levels by 23%. In addition, it appears to reduce insulin resistance. Cardiomyocyte hypertrophy, fibrosis, and death were reduced in mice treated with this peptide than in controls [7]

Diabetes

Oxytocin peptide vial may help treat diabetes by increasing skeletal glucose absorption and insulin sensitivity. In addition, this peptide has been shown to reduce total body fat mass and dyslipidaemia in mice. Obesity is thought to be caused by oxytocin deficiencies even when adequate food consumption and exercise are present, indicating that the peptide is essential in energy balance [8].

Interestingly, oxytocin administration doesn’t seem to have an impact on glucose, insulin, or muscle mass in lean mice. In obese mice, it appears to solely impact specific parameters, indicating that while it may help treat some elements of diabetes, but might not be beneficial for all. Oxytocin appears to have a distinct impact on diabetes than in healthy people. Patients with diabetes who received intranasal oxytocin lost 9 kg in 8 weeks, lowering blood glucose and insulin levels. A1C and insulin sensitivity are negatively linked with circulating oxytocin, according to Barengolts [9].

References

[1] Dayi A, Kiray M, Sisman A, Ozbal S, Baykara B, Aksu I, Uysal N. Dose dependent effects of oxytocin on cognitive defects and anxiety disorders in adult rats following acute infantile maternal deprivation stress. Biotech Histochem. 2019 Oct;94(7):469-480.

[2] Dayi, Ayfer & Cetin, Ferihan & Sişman, et al. The Effects of Oxytocin on Cognitive Defect Caused by Chronic Restraint Stress Applied to Adolescent Rats and on Hippocampal VEGF and BDNF Levels. Medical science monitor : international medical journal of experimental and clinical research.

[3] Yoon S, Kim YK. The Role of the Oxytocin System in Anxiety Disorders. Adv Exp Med Biol. 2020;1191:103-120.

[4] Brüne M. On the role of oxytocin in borderline personality disorder. Br J Clin Psychol. 2016 Sep;55(3):287-304.

[5] Wang P, Wang SC, Yang H, Lv C, Jia S, et al. Therapeutic Potential of Oxytocin in Atherosclerotic Cardiovascular Disease: Mechanisms and Signaling Pathways. Front Neurosci. 2019 May 21;13:454.

[6] Plante E, Menaouar A, Danalache BA, Yip D, Broderick TL, Chiasson JL, Jankowski M, Gutkowska J. Oxytocin treatment prevents the cardiomyopathy observed in obese diabetic male db/db mice. Endocrinology. 2015 Apr;156(4):1416-28.

[7] Jankowski M, Broderick TL, Gutkowska J. Oxytocin and cardioprotection in diabetes and obesity. BMC Endocr Disord. 2016 Jun 7;16(1):34.

[8] Ding C, Leow MK, Magkos F. Oxytocin in metabolic homeostasis: implications for obesity and diabetes management. Obes Rev. 2019 Jan;20(1):22-40.

[9] Barengolts E. OXYTOCIN – AN EMERGING TREATMENT FOR OBESITY AND DYSGLYCEMIA: REVIEW OF RANDOMIZED CONTROLLED TRIALS AND COHORT STUDIES. Endocr Pract. 2016 Jul;22(7):885-94

This product is sold as a research chemical and not for human consumption 

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